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Sources Weight Regain and Cardiometabolic Effects After Withdrawal of Semaglutide: The STEP 1 Trial Extension Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: SURMOUNT-4 PubMed Continued Treatment With Tirzepatide for Maintenance of Weight Reduction Wegovy Prescribing Information FDA Nutritional Priorities to Support GLP-1 Therapy for Obesity Dr
it reflects that robust clinical trials in breastfeeding women are ethically challenging to conduct

[1] [2] For diabetes, it's marketed as Ozempic (injectable, up to 2 mg weekly) and Rybelsus (oral, 7-14 mg daily)

Under the combined influence of stronger evidence, clearer safety boundaries, and patient values, GLP-1RAs may help shift PCOS management from isolated interventions toward a more integrated, life-course-oriented care framework