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In a clinical trial involving individuals with established cardiovascular disease, retatrutide reduced the risk of major adverse cardiovascular events, including heart attacks, strokes, and cardiovascular death

For example, a 2025 study showed an average loss of 7.9 to 12 lbs in PCOS patients

mean eGFR was 65.0 (s.d

In contrast, Semaglutide GLP-1, which is administered weekly, may initially appear more expensive
