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Researchers note the limited number of treatment options for alcohol use disorder, and this study could help determine whether brenipatide becomes a new option pending a future FDA decision

The mean (SD) reduction of body weight from baseline was 4.74 (1.687) kg on day 29 in 15mg dose cohort compared to 0.45 (1.460) kg in the placebo cohort
Plasma total cholesterol (Thermo Fisher Scientific, Infinity Total Cholesterol Reagent, TR13421), triglycerides (total glycerol and triglycerides) (Thermo Fisher Scientific, Infinity Total Triglycerides Reagent, TT22421), non-esterified fatty acids (NEFA) (Invitrogen, non-esterified free fatty acids (NEFA/FFA) Colorimetric Assay Kit, Thermo Fisher Scientific, EEA017), AST (Thermo Fisher Scientific, EEA003) and ALT (Thermo Fisher Scientific, EEA001) were quantified using enzymatic kits according to the manufacturers protocols

[DOI] [PubMed] [Google Scholar] Koole C, Savage EE, Christopoulos A, Miller LJ, Sexton PM, Wootten D
