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Safety and efficacy of once-weekly dulaglutide versus sitagliptin after 2 years in metformin-treated patients with type 2 diabetes (AWARD-5): a randomized, phase III study

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Taking tirzepatide with other medicines to treat diabetes, such as sulfonylureas or insulin, may increase your risk of hypoglycemia

had current treatment with or history of (within 3 months before visit 2) treatment with medications that may cause substantial weight gain, including but not limited to: tricyclic antidepressants, atypical antipsychotics and mood stabilizers Examples: imipramine amitriptyline mirtazapine paroxetine phenelzine chlorpromazine thioridazine clozapine olanzapine valproic acid (and its derivatives) or lithium Note: selective serotonin reuptake inhibitors other than paroxetine were permitted