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1 (2025 ): 400- Glycated hemoglobin (HbA1c) remains the gold standard for assessing long-term glycemic control, reflecting the average plasma glucose over the preceding 812 weeks

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While challenges with adherence, side effects, and weight regain upon discontinuation have prompted the search for additional strategies, targets like GLP-1R, GIPR, and GDF8 (Myostatin) still remain the most highly relevant and active areas of research for developing effective obesity treatments