glp 1 neurotransmitter Glucagon-like peptide-1 Insights into a possible role

Instead of following the standard titration schedule, where you increase your dose every four weeks until you hit the high maintenance level, microdosers stay at the lowest effective dose for months, or even take less than the starting dose

One major area of concern was dosing and formulation variability

It should be noted that the rate of WL with the novel pharmacotherapies could be individualised, something that is not feasible with bariatric surgery, however the optimal WL rate to optimise the risks for nutritional complications and/or cholelithiasis will need further research [107]

GLP-1RAs produce more frequent and severe side effects when administered through larger doses or quicker titration schedules