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Since it is often suggested that the cocaine-induced hyperactivity might be a correlate of dopamine release in the NAc, the lack of an effect of EX4 on cocaine hyperactivity might indicate that the reduction in reward value of cocaine occurs via a mechanism outside of or downstream of the dopamine release

The goal is to create a sustainable long-term plan that supports lasting wellness while minimizing the risk of weight regain

As with previous cost of control analyses, the present analysis is therefore intended to provide complementary information to assist decision-makers with shorter time horizons [18]

Step 2: Allow vials to warm