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Description
The association between glucagonlike peptide1 receptor agonists (GLP1 RAs) and depression remains uncertain due to contradictory evidence

Obesity and Type 2 Diabetes has an increasing prevalence worldwide, presenting a major health challenge

GLP-1 RAs reduce gut motility by slowing gastric emptying and altering the migrating motor complex (MMC), increasing the risk of conditions like gastroparesis and bowel obstruction

Here, the authors review the physiological roles of GLP-1, the potential renoprotective mechanisms of incretin-based therapies and the available renal outcome data from clinical trials.
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