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[12] Gastric acid-suppressing agents (proton-pump inhibitors and H-receptor antagonists) diminish dietary B12 liberation from protein complexes, a pharmacodynamic interaction that can exacerbate underlying deficiency
Current NICE guidance (NG28 for type 2 diabetes and technology appraisals for weight management) does not include recommendations for probiotic use alongside GLP-1 medications , reflecting the absence of robust evidence

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