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You should contact your GP or diabetes specialist if : Your blood glucose control is inadequate : If home glucose monitoring or HbA1c results indicate that your current medication regimen is not achieving target levels, your treatment plan may need adjustment

GLP-1MK-801 also displayed superior weight loss efficacy compared with co-administration of GLP-1 and MK-801, despite having similar effects on food intake (Extended Data Fig

But medical literature evidence suggests these same pathways may interfere with key skin functions by: Slowing fibroblast activity, reducing the production of structural proteins like collagen and elastin Decreasing cell turnover, leading to dullness and slower skin renewal Compromising the skin barrier, increasing water loss and sensitivity to environmental damage The result