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The standard semaglutide protocol increases the dose every 4 weeks, but some patients benefit from staying at a lower dose for 68 weeks before advancing

The FDA boxed warning specifically contraindicates certain GLP-1 receptor agonists in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2)

Report any suspected side effects to your healthcare provider and consider reporting them through the MHRA's Yellow Card scheme (yellowcard.mhra.gov.uk), including during pregnancy or breastfeeding

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