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Description
The SUMMIT trial, involving 731 individuals with HFpEF and obesity followed for a median of 104 weeks, revealed a 38% decrease in the composite endpoint of cardiovascular mortality or heart-failure deterioration events (HR: 0.62, 95%CI: 0.41-0.95, P = 0.026), driven primarily by fewer worsening heart-failure events (8.0% vs

What were seeing is a meaningful shift in how chronic conditions are managed and how outcomes are ultimately shaped

10.1001/jama.2016.1252 47 LingvayI.DesouzaC

and a real signal of euglycaemic ketosis (raised ketones with normal glucose) means ketone monitoring stays standard of care
