why have i not lost weight on semaglutide am losing (Ozempic/Wegovy)? Semaglutide for weight loss -

Beyond local effects, LPS signaling feeds back to metabolic organs, worsens insulin resistance and dyslipidemia, and realigns bile-acid and choline pathways in parallel with microbiota shifts 5

GLP-1 medications are primarily used to treat type 2 diabetes and are also prescribed for chronic weight management in patients with obesity or related health risks

Weight changed from 196 lbs in the before picture to 173 lbs in the after picture

This difference primarily stems from bioavailability: injectable semaglutide enters circulation directly, while oral semaglutide faces significant absorption challenges in the digestive tract