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High levels of IL-1 have been reported in freshly homogenized colonic biopsies taken from IBD patients

There is growing evidence indicating that GLP-1 activates both Gq and Gs signalling pathways, whereas the effects of GIP and GCG are mediated exclusively through Gs [13]

Observational data among patients with alcohol use disorder (AUD) and comorbid diabetes or obesity suggests that GLP-1 RAs use may be associated with reduced risk of AUD-related hospitalization (19)
