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Changes in DPP-4 activity is associated with obesity and DMT2 as well as other neurologic and inflammatory diseases

Growing evidence from observational studies indicates that treatment of obesity with bariatric surgery improves cardiovascular outcomes, but these findings have not been confirmed in randomized trials, largely because of randomization challenges with bariatric surgery

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Clinical trials and studies have shown that skin-related side effects, although not very common, can occur in some individuals using semaglutide