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Studies show that patients taking tirzepatide can lose up to 15-20% of their total body weight over time
In contrast, GIP positively stimulates glucagon secretion at lower levels of glycaemia (Seino et al, 2010)
Supresa works through serotonin modulation, promoting natural satiety signals rather than forced appetite suppression
These findings suggest that growth hormone therapy during childhood and/or adolescence may lead to a better metabolic profile in adults with PWS who have del15q, but not in those with mUPD, thus lessening the phenotypic impact of the deletion
