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Description
Clinically relevant effects have been mainly observed for orally administered drugs with a narrow therapeutic window, relying on rapid absorption, such as oral contraceptives, for which tirzepatide decreased both C max and AUC
Wegovy in 2021), meaning there isnt a lot of long-term safety data available
In that case, common approaches include spacing injections every other week for a set period, then reassessing or reducing the weekly dose while closely monitoring weight and glucose levels
Pro: It avoids any potential interference with your work schedule
