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Treatment with tirzepatide in adults with pre-diabetes and obesity or overweight resulted in sustained weight loss, and nearly 99% remained diabetes-free at 176 weeks | Eli Lilly and Company

A body mass index (BMI) over 30, or a BMI over 27 along with other comorbidities, was required to participate

Association of physical weight statuses defined by body mass index (BMI) with molecular subtypes of premenopausal breast cancer: A systematic review and meta-analysis

As with other medications, prescribers may prescribe these medications for off-label purposes, provided it aligns with the accepted standard of care and falls within their scope of practice