does semaglutide work for weight loss Weight Loss with Semaglutide, Tirzepatide

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Caroline Apovian, an endocrinologist who co-directs the Center for Weight Management and Wellness at Brigham and Women's Hospital in Boston, says that she doesn't use metformin "too much" for non-diabetic patients seeking weight loss these days

The starting dose of semaglutide was 0.24 mg once weekly, increased every 4 weeks (to once-weekly doses of 0.5, 1.0, 1.7, and 2.4 mg) until the target dose of 2.4 mg was reached after 16 weeks

Tirzepatide's dual action on GLP-1 and GIP receptors often requires a slightly more cautious titration pace, as GIP activation can enhance nausea in some patients during the first few weeks