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Beyond weight-related improvements, it enhances insulin sensitivity (HOMA-IR reduction of 1.58), lowers fasting blood glucose by 0.30 mmol/L , and boosts SHBG levels by 10.04 nmol/L , which helps address hyperandrogenemia and its associated symptoms

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Someone who loses 12% of their body weight over six months on a medication they can stick with will always do better than someone who loses 18% in trials but stops after eight weeks because the side effects, cost, or daily routine became too difficult

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