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These impacts include increasing neuron progenitor cells proliferation, prolonging potentiation in the hippocampus, improving learning, as well as reducing plaque formation and inflammation in the brain ( swe /PS1_E9 (APP/PS1) mouse model after using LG ( Box 2 Protein kinase C (PKC), as a family of protein kinase enzymes, plays a vital part in several signal transduction cascades and have the ability to regulate other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues