surmount-1 tirzepatide obesity nejm 2022 weight loss percent Trial Tirzepatide vs Semaglutide for Weight
Description
RESULTS 3.1

doi: 10.1038/348555a0 16 KudelkaAPLevyTVerschraegenCFEdwardsCLPiamsomboonSTermrungruanglertWet al
Tirzepatide should be used with caution in patients taking oral contraceptives due to delayed gastric emptying

The combination with tirzepatide can amplify both the GI and energy-related side effects
