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Below 7.0%: Standard target for most adults with diabetes Below 6.5%: More aggressive target for some patients Below 5.7%: Normal range (non-diabetic) 87% of Retatrutide trial participants reached the 7.0% target Metformins A1C reduction typically falls in the 1.0-1.5% range when initiated as first-line therapy

In 2020, the total combined direct cost of overweight and obesity in South Africa was estimated to exceed R33 billion, according to research conducted by the SAMRC and Wits Centre for Health Economics and Decision Science (PRICELESS SA)

The bi-weekly dosing regimen further reduces the annual number of injections by 50% compared to mainstream once-weekly GLP-1RAs