glp 1 drugs how long have they been around The popularity of GLP-1 has exploded. Once a relatively obscure class of drugs prescribed for people with diabetes, GLP-1s now shown an impressive ability to treat obesity, which affects over GLP-1 Genetics: How Genes Affect
Description
Curr Biol
[49] observed significant reduction in hs-CRP with twice-daily exenatide, and DURATION-2, DURATION-3, DURATION-3 extension, and DURATION-5 studies observed considerable reductions in inflammatory markers such as hs-CRP or CRP (Table 2) [484950515253545556575859606162636465666768697071727374757677787980818283848586]
Hypoglycaemia risk may be elevated in certain patients
Genetic analyses in mice suggested that these actions were mediated through central nervous system GLP-1Rs and associated with the induction of POMC and leptin receptor expression in the arcuate nucleus [112]
