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Patients should never combine these medications without explicit guidance from their prescribing clinician , who can monitor for potential complications and adjust treatment plans accordingly

If you have obesity and are considering treatments that can lead to significant weight loss, you may be wondering how the two leading options compare: bariatric surgery, which permanently alters the digestive tract, versus powerful new appetite-suppressing medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound)

While many users tolerate the medication well, individual responses can differ

Inject as soon as you remember, then resume your normal weekly schedule