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Risk factors for GLP-1 face All patients who take GLP-1 agonist medications or embark on weight loss are at risk of these facial changes
GLP-1RAs may directly or indirectly activate the sympathetic nervous system

These findings provided a better understanding of the physiology of GLP-1 and the pharmacology of its analogues and have revolutionized the management of obesity and several comorbidities

There have been rare postmarketing reports of pulmonary aspiration in patients receiving GLP-1 receptor agonists undergoing elective surgeries or procedures requiring general anesthesia or deep sedation who had residual gastric contents despite reported adherence to preoperative fasting recommendations
