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Description
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From a purely theoretical pharmacological standpoint, there is no known direct interaction between these compound classes
These dual or triple agonists represent the next frontier in obesity pharmacotherapy
Molecular durability is achieved through peptide engineering strategies that (i) confer resistance to DPP-4 cleavage, typically via N-terminal modification, and/or (ii) extend systemic exposure through fatty-acid acylation, which enhances albumin binding and slows renal clearance, thereby prolonging receptor activation [18]
