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In addition to the trial results released on April 27, a clinical trial published in the New England Journal of Medicine last year showed that patients who were obese or overweight and had other health conditions such as high blood pressure, high cholesterol, or cardiovascular disease lost 20% of their body weight in 16 months while taking the maximum dose of 15mg

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"Your body develops this kind of compensation, and when you hit it in two different places, you get a better result," Aronne said

Tirzepatide dosing chart (FDA-approved schedule): Start at 2 } Tirzepatide Dosing at a Glance The FDA-approved tirzepatide dosing schedule follows this pattern: Per FDA labeling for both Mounjaro (type 2 diabetes) and Zepbound (weight management), initiation is 2 } Compounded Tirzepatide Dosage: What's Different