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These combined actions reduce abnormal electrical activity in the brain, which underlies its efficacy in epilepsy and migraine prevention

In a mouse model of 5-fluorouracilinduced mucositis, daily treatment with 3 nmol/kg tirzepatide for 7 days, but not 41 g/kg semaglutide, significantly reduced ileal neutrophil elastase staining (89)

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In summary, combining the results of preclinical and clinical studies, GLP-2 has been proven to play a significant role in inhibiting bone resorption but has little effect on bone formation, thus promoting the increase of BMD