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Discontinuation and reinitiation patterns are not well understood
126 Co-administration of warfarin (a substrate of CYP1A2, CYP2C9, and CYP3A4) and octreotide led to high INR levels in humans, which may be attributed to the increased warfarin exposure caused by octreotides inhibitory effect on CYP3A4
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No sample size calculation was performed for any study, however, for all studies, we typically start with an n = 10, which is usually sufficient to see statistically different changes between the groups, as well as a sufficient sample size for subsequent analyses on tissues and serum
