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Therefore, the aim of this review of published data is to compare the magnitude and duration of the effects on HR induced by various GLP-1 RAs, both in healthy individuals and in those with T2DM, utilizing individual 24-h HR measurements from clinical trials, including head-to-head comparison data

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95% CI 0.31, 0.84) in favour of orally administered semaglutide was observed

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Structural alterations of the ligand peptides as in GIP/GLP-1 dual-receptor agonists may alter these cellular processes strongly and may explain that an antagonist may activate while an agonist may block receptor signaling (4649)

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