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Description
The number of therapeutic options is limited and are often associated with adverse side effects
Purpose of Review Despite the great progress in obesity-tackling strategies, a negative energy equilibrium between energy expenditure and energy intake remains the cornerstone in obesity management

While the clinical effects of tirzepatide have been very encouraging, important questions remain as to the mechanism of action
GLP-1 receptor agonistswidely recognized for their ability to aid weight loss and improve blood sugar controlhave quickly gained popularity in recent years
