6 weeks of semaglutide How Long Does It Take for Semaglutide to Work? Woman With PCOS Takes Semaglutide:
Description
The "not localized to the injection site" part is important
What the Evidence Says About Taking Wegovy with Statins Clinical trial data supports the safe concurrent use of Wegovy and statins
Constipation was less common than with some single-target GLP-1 compounds, possibly due to the glucagon component stimulating gut motility

Many patients need 6 to 12 months or longer