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The Market Effects of Weight-Loss Drugs Have Only Just Begun Nonetheless, so startling and immediate is the financial impact for manufacturers that Lars Fruergaard Jorgensen, A/S CEO of Novo Nordisk the Danish company that manufactures Ozempic reported fielding calls from executive counterparts at food companies who were wary (and worried) of the long-term impact of the weight-loss drugs on their businesses

Some of our active ingredients are also used for the long-term treatment of type 2 diabetes and can be taken for years if necessary

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Isis (now Ionis) ran antisense programs against glucagon receptor expression, also showing efficacy but accompanied by hepatic steatosis findings that aligned with the small-molecule class