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If you mean: most established and widely used the answer is semaglutide

However, factors such as dehydration , certain foods, and urinary tract infections are more common culprits in altering urine scent

For example, In The Dhurat Study (2013)

For most eligible patients, GLP-1 medications are considered safe when: Prescribed by a licensed healthcare provider Initiated at appropriate doses Gradually titrated Monitored regularly These medications have undergone large clinical trials and have more than a decade of safety data in diabetes management
