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Comparative efficacy, tolerability, and acceptability of donanemab, lecanemab, aducanumab, melatonin, and aerobic exercise for a short time on cognitive function in mild cognitive impairment and mild Alzheimer's disease: a systematic review and network meta-analysis
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Titrating slowly, spending at least 4 weeks at each dose level, dramatically reduces GI burden

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The discrepancy could reflect the need for larger datasets, says Andrea Ganna, a Harvard Medical School geneticist and co-author of the Nature Medicine paper
