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Moreover, treatment groups significantly differed in disease duration at baseline as most patients have not decided for the treatment with GLP-1-RAs until having failed to achieve significant weight loss on their own, which could have affected our results

However, Tresiba remains essential for patients who need direct insulin replacement, particularly those with type 1 diabetes or advanced type 2 diabetes with significant beta cell failure

10.1093/ajcn/82.5.923 28 WatersD

It is registered by the Therapeutic Goods Administration (TGA) as a treatment for type 2 diabetes
