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Food and Drug Administration (FDA) approved Zepbound for use in chronic weight management by adults with obesity, and by adults with overweight plus at least one weight-related health issue, such as high blood pressure, type 2 diabetes, or elevated cholesterol

Some were then randomized to receive either additional fast-acting insulin (insulin lispro) or one of three different doses of tirzepatide (5mg, 10 mg, or 15mg)
