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In that study, exendin-4 not only ameliorated albuminuria but conferred kidney structural benefits including reduced glomerular hypertrophy and mesangial matrix expansion in the absence of an effect on body weight, blood pressure, or circulating glucose concentrations
Weight loss is not usually sustained over time after you stop taking them
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Ligumsky H., Wolf I., Israeli S., et al., The PeptideHormone GlucagonLike Peptide1 Activates cAMP and Inhibits Growth of Breast Cancer Cells, Breast Cancer Research and Treatment 132 (2012): 449461
