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Clinical trial data from the NEJM Phase 2 study showed that gastrointestinal events were predominantly mild to moderate, occurred primarily during dose escalation, and were partially mitigated by starting at 2mg rather than 4mg

10.1093/eurjhf/hfq121 46 LamC

doi: 10.1016/j.clinthera.2011.04.024

BMJ, 2024
