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Description
Enzyme selectivity for cleavage immediately C-terminal to proline or alanine residues at position 2 substrate peptides is dictated by the shape and size of the S1 pocket, which is lined by Val656, Tyr631, Tyr662, Trp659, Tyr666, and Val711 (Figure 6)
Reference List Clinical Obesity
For age-related macular degeneration, findings were dichotomous, suggesting a protective effect against non-exudative forms but a potential increased risk for neovascular disease
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