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Description
In the STEP 1 trial extension, people who came off semaglutide regained around two-thirds of the weight they had lost within a year (Wilding et al., 2022)
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By controlling for BMI, diabetes, and other health factors, the study strengthens the link between GLP-1 exposure and enhanced sperm count, suggesting a potential therapeutic role for GLP-1s in male infertility management
These results reflect sex-specific patterns of fat distribution and differential response to liraglutide, with reductions in visceral adiposity strongly correlated with decreases in AC across both sexes
