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Finally, the insulinotropic actions of GLP-1 are preserved even in diabetic patients, although type 2 diabetes diminishes the same actions that GIP exerts in humans [30,32]
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Some people report feeling tired, but sleepiness is not considered one of the most common effects observed in clinical studies
Liraglutide depolarizes membrane potential and increases the spontaneous action potentials directly through postsynaptic GLP-1R in the ARC neurons expressing POMC (Secher et al., 2014
