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To boldly go where no GLP1RA has gone before @novonordisk swings for the fences and initiates 2 phase Phase 3 two year trials for oral 14 mg semaglutide #Alzheimers disease

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GLP-1 in the periphery (outside the CNS) has been shown to act on the brain to reduce food ingestion

Novo Nordisk has announced headline results from the STEP UP study, a phase 3b trial in the global STEP programme, which revealed the trial achieved its primary endpoint by demonstrating a statistically significant and superior weight loss at week 72 with semaglutide 7.2mg versus placebo.STEP UP is a 72-week efficacy and safety trial investigating subcutaneous semaglutide 7.2mg compared to semaglutide 2.4mg and placebo, all administered once weekly