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91 In UC patients, endoplasmic reticulum function may be impaired, leading to abnormal accumulation of intracellular proteins and exacerbation of the cellular inflammatory response
In June 2023, the American Society of Anesthesiologists (ASA) issued consensus-based guidance warning that GLP-1 drugs can delay gastric emptying and may increase the risk of regurgitation and pulmonary aspiration (stomach contents entering the respiratory system) during anesthesia
bias towards -arrestin-induced desensitization is an additional factor that could explain the reduced insulinotropic efficacy of this compound
