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Statistical analyses Data are expressed as scattered plots or means +/ standard error (SE) or standard error of the mean (SEM)
A randomized, double-blind, placebo-controlled trial of resveratrol with glucose and malate (RGM) to slow the progression of Alzheimers disease: A pilot study

A further study presented at Digestive Disease Week 2025 of 993 patients found GLP-1RA to be associated with a statistically significant increase in clinical remission rates (HBI or Mayo score) at 3 months numerical at 6 and 12 months without an increase in side-effects

The logic is that bupropion + naltrexone (Contrave) addresses reward-driven eating and appetite, while topiramate independently suppresses cravings through a different brain mechanism
