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HR 1.19, 95% CI 0.91.58), but not for the other DPP-4 inhibitors as in the TECOS study for sitagliptin (HR 1.00, 95% CI 0.831.20) or the CARMELINA study for linagliptin (HR 0.90, 95% CI 0.741.08) (57, 62, 64, 65, 68)
Nevertheless, an excessive metformin dosage could result in lactic acidosis and additional adverse reactions in individuals with one or more risk factors for lactic acidosis (Misbin et al., 1998)
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Eat Balanced, Small Meals Even with reduced appetite, focus on nutrient-rich foods
