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TRIUMPH-3 required a BMI of 35 or higher
The CSF-to-plasma ratio is approximately 0.4%, confirming that a small but definite amount of the drug penetrates the central nervous system (CNS) ( 4 Preclinical evidence: a foundation of neuroprotection The considerable interest in semaglutide as a neurotherapeutic agent is derived from a robust body of preclinical evidence
Always consult with a qualified healthcare provider before starting, stopping, or changing any medication regimen
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