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In connection with ongoing litigation, the FDA clarified that it does not intend to enforce violations of the Federal Food, Drug, and Cosmetic Act (FD&C Act) related to tirzepatides compounding for a limited time to prevent unnecessary treatment disruptions: State-licensed pharmacies (Section 503A) : Permitted to compound, distribute, or dispense tirzepatide injections until February 18, 2025 (60 calendar days from todays announcement)

Aim for a minimum of 64 ounces of water daily, more if you exercise or live in a hot climate

The concern is entirely about the broader medication context in which the combination sits

Your healthcare provider may decide to recommend a lower dose of cyclobenzaprineor prescribe a different drug altogether