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GLP-1 peptides may degrade through oxidation, deamidation, hydrolysis, or isomerization reactions

These changes were accompanied by preservation of structural proteins including aggrecan and collagen II, along with reduced caspase-3mediated apoptosis, suggesting a coordinated reduction in glycation-driven cellular stress and tissue degradation

doi: Catanese L

Even more telling is that a substantial number of individualsfrom 20.7% to 68.4%lost more than 10% of their initial body weight
